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2026

Isabella N. Grabski, Junsuk Lee, John Blair, Carol Dalgarno, Isabella Mascio, Alexandra Bradu, David A. Knowles, and Rahul Satija. “Mapping transcriptional responses to cellular perturbation dictionaries with RNA fingerprinting.” Cell.

Han Dong, Arindam Ray, Lara K. Rotter, Jinhua Wang, Isabella N. Grabski, Heemaja Mewada, Lulu Wang, Kun Huang, Ye Tian, Maxime Meylan, Graham Barlow, Chenyang Yu, Mahesh Raundhal, Sung-Hee Yoon, Shreya Nakhawa, Liya Ding, Jean J. Zhao, Ursula A. Matulonis, Marc Foretz, Kai W. Wucherpfennig, Rafael A. Irizarry, Marc N. Wein, and Laurie H. Glimcher. “Inhibition of salt-inducible kinases reprograms T cells and antitumor immunity in ovarian cancer.” Nature Immunology.

Isabella N. Grabski*, Jaime L. Schneider*, Sara Hanahan, Arvind Ravi, Justin F. Gainor, Kevin M. Haigis, Rafael A. Irizarry, and Marcia C. Haigis. “Aging dictates tumor-specific genomic alterations across cancer types.” npj Aging.

Moon Hee Yang, Shikha Sheth, Bing Shui, Isabella N. Grabski, Samuel Seongmin Park, Ana Cobo, Rafael A. Irizarry, John V. Heymach, Lukas E. Dow, and Kevin M. Haigis. “The impact of K-Ras Gly12 mutants on homeostasis and tumorigenesis in the colonic epithelium.” Oncogene.

Alexandra Bradu, John D. Blair, Isabella N. Grabski, Isabella Mascio, Junsuk Lee, Cecilia McCormick, and Rahul Satija. “Genome-wide single-cell perturbation screens with VIPerturb-seq.” bioRxiv.

2025

Isabella N. Grabski, Lorenzo Trippa, and Giovanni Parmigiani. “Bayesian multi-study non-negative matrix factorization for mutational signatures.” Genome Biology.

Roberta De Vito, Blake Hansen, Isabella N. Grabski, Lorenzo Trippa, and Giovanni Parmigiani. “Analysis of mutational signatures in multiple cancer studies: Recent Bayesian tools.” Journal of Cancer Biology.

Longda Jiang, Zhixin Cyrillus Tan, Isabella N. Grabski, Yuhan Hao, Nathan Nakatsuka, Sourav Sarkar, Anagha Shenoy, and Rahul Satija. “Reconstructing developmental and disease progression with sample-level embeddings.” bioRxiv.

John D. Blair, Alexandra Bradu, Carol Dalgarno, Isabella N. Grabski, and Rahul Satija. “Iterative, multimodal, and scalable single-cell profiling for discovery and characterization of signaling regulators.” bioRxiv.

Blake Hansen, Isabella N. Grabski, Giovanni Parmigiani, and Roberta De Vito. “Bayesian probit multi-study non-negative matrix factorization for mutational signatures.” arXiv.

2024

A. Katie Maurer*, Isabella N. Grabski*, Roch Houot, Satyen H. Gohil, et al. “Baseline immune state and T-cell clonal kinetics are associated with durable response to CAR-T therapy in large B-cell lymphoma.” Blood.

Isabella N. Grabski, John V. Heymach, Kenneth L. Kehl, Scott Kopetz, Ken S. Lau, Gregory J. Riely, et al. “Effects of KRAS genetic interactions on outcomes in cancers of the lung, pancreas, and colorectum.” Cancer Epidemiology, Biomarkers & Prevention.

2023

Isabella N. Grabski, Kelly Street, and Rafael A. Irizarry. “Significance analysis for clustering with single-cell RNA-sequencing data.” Nature Methods.

Isabella N. Grabski, Roberta De Vito, Lorenzo Trippa, and Giovanni Parmigiani. “Bayesian combinatorial MultiStudy factor analysis.” Annals of Applied Statistics.

2022

Isabella N. Grabski and Rafael A. Irizarry. “A probabilistic gene expression barcode for annotation of cell types from single-cell RNA-seq data.” Biostatistics.